Valine

Valine

Valine

Formal Name: 2-amino-4-methylvaleric acid
Supplement Forms: Pills, food, liquid

Recommended Daily Allowance

  • Infants: (0 to 12 Months) 89 mg/kg of body weight
  • Children: (1 to 13 years) N/A
  • Adolescents: (14 to 18 Years) N/A
  • Adults: (19 and Older) 14 mg/kg of body weight
  • Lactating Women: N/A
  • Pregnant Women: N/A

Notes: mg stands for milligrams and kg stands for kilograms.

Additional Information

Valine was initially isolated in 1901 from casein protein. It makes up one third of the branched-chain amino acids which also includes leucine and isoleucine. Together, these amino acids make up nearly 70% of the total amino acids within the proteins of the body.

Bodily Functions Valine Assists

As part of the branched-chain amino acids group, valine is integral in preventing excess protein degradation in muscular protein and improves synthesis of muscle protein in order to aid in muscular rebuilding. Valine also has the added benefit of helping in the detoxification of excess ammonia. When used in a combination of phenylalanine-valine-methionine-tryptophan at a 3:2:2:1 ratio, it has been known to reduce food intake by 50% in obese women when taken at 4 gram doses before meals.

Symptoms Of Deficiency:
  • Deficiency in valine is rare.
  • However, an inability to metabolize valine,
    leucine and isoleucine is identified as maple syrup
    urine disease which can result in myelination
    damage of the nerves.
Foods High In Valine

Foods high in valine include cheese, fish, red meats, poultry, peanuts, sesame seeds and lentils. Additionally, valine can be found in adequate amounts of mushrooms, soy beans, whole grain cereals, legumes and peas.

Ailments That Valine Helps Against:
  • Used in treatment of hepatic encephalopathy
  • Useful in treatment of degenerative neurological conditions
  • Helpful against gallbladder and liver diseases
  • May help in arthritis treatment
Side Effects And Toxicity

Those with kidney or liver disease should consult a doctor before supplementing with this amino acid. High doses of valine may result in hallucinations and a crawling sensation on the skin.

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